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Smoking cigarettes and drinking excessive amounts of alcohol may negatively affect collagen production, as does following a diet high in ultra-processed foods and added sugar

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The cancelled Phase I trial was not buried by a regulator

Patients should prioritize protein intake to preserve lean body mass during weight loss, aiming for 1.0-1.5 grams per kilogram of ideal body weight daily (lower for those with chronic kidney disease), distributed across meals

To conserve energy, the body trims unneeded muscle and preserves energy-dense fat