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(PubMed) Hobbs RP, Bernstein PS
The reference standard is scintigraphy : a test meal is labeled with a radioisotope, and a gamma camera tracks how quickly the labeled contents leave the stomach, yielding a half-emptying time (the T values quoted earlier for pramlintide came from this class of method)
32 Efflux lowers the intracellular drug concentration below inhibitory levels
GSH is at 110 mM concentrations in all mammalian tissues (highest concentration in liver) as the most abundant non-protein thiol that protects against excessive oxidative stress
Betaine's special thing is being an osmolyte , a molecule that helps to control cell-water balance
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