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DPP-4i could restore the inactivation of AKT and ERK signaling and inhibit NF-B activation to reduce the production of pro-inflammatory factors, including TNF-, IL-1, monocyte chemoattractant protein-1 (MCP-1), ICAM-1 and TGF- (169, 170)
Patients using oral contraceptives should be advised to switch to a non-oral method or add a barrier method for 4 weeks after tirzepatide initiation and after each dose increase
Clinical trials support its efficacy, demonstrating significant weight loss when combined with lifestyle adaptations
Resistance to leptin, the satiety hormone, is considered a prominent driver of obesity
KANSAS CITY The growing prevalence of GLP-1 medications is continuing to shape innovation in the food and beverage industry
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