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Common (1-10 in 100 people): vomiting, constipation, stomach pain, injection-site redness, fatigue, mild low blood sugar when used with other diabetes drugs

SURMOUNT-OSA Obstructive Sleep Apnea In two phase 3 trials enrolling 469 adults with moderate-to-severe OSA and obesity, tirzepatide reduced apnea-hypopnea index (AHI) by approximately 25 events per hour versus 5 events per hour with placebo about five times the effect of placebo

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doi: 10.2147/iprp.s103494 59 SchnrichG.RafteryM

This results in a darker complexion