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GLP-1 RAs were identified in the DRUG files using generic or brand names, including exenatide (BYETTA, BYDUREON BCISE), liraglutide (VICTOZA, SAXENDA, XULTOPHY), lixisenatide (LYXUMIA, ADLYXIN, SOLIQUA), dulaglutide (TRULICITY), semaglutide (OZEMPIC, RYBELSUS, WEGOVY), and tirzepatide (MOUNJARO, ZEPBOUND)
GLP-1 is an incretin hormone that is secreted by intestinal L cells in response to nutrient ingestion
Mounjaro is FDA approved for Type 2 diabetes because it helps the pancreas make more insulin to lower blood glucose
Long-Acting strategies for GLP-1 RAs, source: Designing a Dual GLP-1R/GIPR Agonist from Tirzepatide: Comparing Residues Between Tirzepatide, GLP-1, and GIP, Drug Design, Development and Therapy, Oral Formulation The only available oral GLP-1RA is semaglutide (Rybelsus, Novo Nordisk)
For comparison of options, see our Mounjaro vs Ozempic guide
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