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Microarray analysis has identified GHR as one of the top eight genes upregulated by BPC-157, with a 2.29-fold increase in expression
Also, a similar protocol was successful in the therapy of the other fistulas, that is, gastrocutaneous (Skorjanec et al., 2009), esophagocutaneous (Skorjanec et al., 2015), vesicovaginal (Grgic et al., 2016), and rectovaginal (Seiwerth et al., 1997
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In these studies, BPC-157 has shown a notably high LD50 (the dose lethal to 50% of test animals is very high or not reached), suggesting low acute toxicity in rodents
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