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This narrative review summarizes the current clinical evidence on GLP-1RAs in PsO and PsA and discusses future research directions aimed at evaluating their potential role in intercepting PsA development and improving outcomes in patients with complex immunometabolic profiles

Xie C, Jin J, Lv X, et al

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However, various observational studies have shown that metformin may even lead to a reduction in mortality in patients with heart failure [60], so according to current understanding, metformin can be considered a safe drug for patients with diabetes and heart failure