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In a two-year randomized trial in older adults, MK-677 raised IGF-1 into a youthful range and increased fat-free mass by about 1.1 kg versus a small loss on placebo (Nass et al., Annals of Internal Medicine, 2008)
Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factors
If the numbers look good because of medication, but the underlying condition, excess visceral fat, insulin resistance, chronic inflammation, hasn't changed, what exactly have we improved
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