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We have reviewed previously the mechanistic explanations of how these multiple IO&NS pathways cause neuroaffective toxicity and, consequently, the onset of chronic fatigue syndrome and somatic and affective symptoms [28, 31, 81, 112,113,114]

Women may experience more regular cycles and improved luteal phase function

Oral administration of l-carnitine (3 g/d) with omega-3 fatty acids could increase carnitine palmitoyl-transferase-I activity and relieve clinical symptoms of CFS 642

Thus, low vitamin B12 levels may contribute to obesity

The broader role of peptides in lupus management is an evolving field worth following