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Alternative metrics: when BMI is not the whole story BMI is the gatekeeper, but it is not the only measure of whether you would benefit from GLP-1 therapy

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FIGURE 2: FDA-APPROVED GLP-1 RA MEDICATIONS Source: FDA-approved labeling for each medication (as of March 2025) You can calculate your BMI from height and weight using this online BMI calculator[archived link]

Clinical trials show that tirzepatide's weight loss benefits increase across dose ranges, with some studies reporting 20% or greater body weight reduction at higher maintenance doses