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The combination can be particularly effective for patients with significant insulin resistance

Vomiting or diarrhea that prevents fluid intake can become dangerous

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A recent matched-cohort study (in the journal JAMA Ophthalmology) looked at 16,827 patients (with type 2 diabetes or overweight/obesity) and found that people prescribed semaglutide had a higher incidence of NAION than matched patients on other medications

Ozempic is more widely used overall, but Saxenda is one of the few FDA-approved injectable medications for weight loss