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Medical spas and dermatology clinics use GLP-1 prescriptions alongside complementary treatments such as body contouring, radio-frequency (RF) microneedling, and even injectable biostimulators to aim for aesthetic changes, for example, facial volume loss, linked with rapid weight loss

Keep in mind that, again, GLP-1s arent for everyone who simply wants to lose weight: Theyre often prescribed to treat obesity, a chronic condition in which you have a body-mass index (BMI) of 30 or higher

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Skin sensitivity is less common than the classic GI side effects but can be more psychologically distressing because it is less understood and less frequently discussed

At the same time, the natural aging process itself contributes to: Progressive collagen degradation Loss of elastin fibers Thinning of the dermis Reduced skin elasticity When fat loss from GLP-1 therapy intersects with these age-related changes, the face may appear less supported, even if the skin itself remains healthy