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Because calorie intake ultimately drives changes in body composition, even modest appetite modulation could influence weight trends
Its efficacy was confirmed by a meta-analysis published recently in the Mayo Clinic Proceedings
Fiber Intake Predicts Weight Loss and Dietary Adherence in Adults Consuming Calorie-Restricted Diets: The POUNDS Lost (Preventing Overweight Using Novel Dietary Strategies) Study
A 50% dose reduction (0.5-1 mg subcutaneously, 3 times per week maximum) is a reasonable starting point
And track your rotation carefully to avoid revisiting recently used spots
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