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Any specific decimal-precision number cited without a human PK study should be treated as speculative

The review also noted that GHK-Cus copper complexation ability raises Cu2+ penetration rates across the stratum corneum, and documented the development of formulation innovations including the TriHex peptide system that combine GHK-Cu-type tripeptides with hexapeptides to produce synergistic upregulation of regenerative genes and suppression of aberrant collagen deposition

This reduces pain and lowers the chance of problems

behavior modification strategies were recommended as needed