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[Low et al 2007 1] [18] Function [edit] The activity of GSTs is dependent upon a steady supply of GSH from the synthetic enzymes gamma-glutamylcysteine synthetase and glutathione synthetase, as well as the action of specific transporters to remove conjugates of GSH from the cell

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Large-scale ferroptotic spread may emerge from the cumulative effect of repeated local transmission events, whereby oxidative stress is regenerated from one cell to the next