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The effective commercial protection period is the later of the patent and regulatory exclusivity termination dates in each jurisdiction

In diabetes, high glucose levels lead to the formation of AGEs, which can accumulate in the brain and contribute to A aggregation and tau phosphorylation, both of which play pivotal roles in AD pathology

It is required for the biosynthesis of antibodies, cytokines, and regulatory enzymes, though the specific cellular signaling pathways involved require further targeted study

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