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Acknowledgments We thank Biorender.com for providing fundamental materials of the scheme figures (Figure 4A and Figure 6B)

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Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia Email: [email protected] ORCID: Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Affiliation: 2 American MD Program, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Affiliation: 1 Faculty of Medicine, Tbilisi State Medical University, Tbilisi 0186, Georgia ORCID: Explor Cardiol

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