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CagriSema: A Dual-Target Therapy for Obesity and Type 2 Diabetes Novo Nordisk unveiled the Phase 3 results from the REDEFINE 1 and REDEFINE 2 studies of CagriSema, a fixed-dose combination of cagrilintide (an amylin analog) and semaglutide

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Most surgical guidelines recommend pausing semaglutide 24 to 48 hours before elective procedures, though the exact timing varies by surgery complexity and anesthesia type

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism

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Triple agonists combining GLP 1, GIP and glucagon receptor activity represent another frontier with early data suggesting these may produce even greater weight loss and metabolic improvements

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