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Mitochondrial dysfunction, impaired axonal transport, and neuroinflammation are key contributors to oxidative stress in ALS [169]

One documented case described a researcher who, after 1.5 weeks, noticed dramatic improvement, and by week 4 could perform a kneeling-to-handstand transition without the shoulder pain that had previously made this impossible

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In summary, biologic approaches provide more target specificity and can harness or mimic the bodys own regulatory mechanisms

W., Scofield, M