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Starting at a lower initial dose (for example, 2 mg instead of 4 mg) also helped partially reduce these GI symptoms, andas with other GLP-1 medicationsthe dose was gradually increased over time to improve tolerability
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1996;270(2 Pt 1):E209-14.
ArGLP-1 also reduced total mortality (HR 0.88, 95% CI 0.820.94, p = 0.0001) and hospital admission due to heart failure (HR 0.89, 95% CI 0.820.98, p = 0.013), all without increasing the risk of severe hypoglycemia, pancreatic problems or retinopathy.87 A recent post hoc analysis of CVOT with semaglutide has shown a gain in time free of cardiovascular disease of 1.7 years in those patients with CKD vs
[PMID: 6280867] PubMed record related to this compound for laboratory literature review
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