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40 Therefore, current data suggest that GLP-1 RAs do not improve exercise capacity in HFrEF

The FDA has documented cases of dosing errors and adverse events with compounded semaglutide

Some telehealth and compounding businesses have changed, limited, or discontinued GLP-1-related offerings as FDA enforcement and shortage-list conditions have shifted

In this context, the data currently available on tirzepatide, showing its efficacy in glycemic control to the extent that a considerable percentage of patients achieve glucose levels indicative of diabetes remission [3, 59], as well as its high effectiveness in weight management, are promising regarding its future use in clinical practice