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Research applications for MT-1 span photoprotection biology, melanogenesis studies, wound healing research (MC1R is expressed on keratinocytes and fibroblasts), anti-inflammatory research, and comparative melanocortin receptor studies where MC1R-specific activity must be isolated from MC4R-mediated CNS effects
In contrast to the positive findings observed with elamipretide, outcomes of trials investigating other agents targeting mitochondrial function or related pathways have been inconsistent
It also reduces skin inflammation, eczema and improves skin elasticity
Unlike older GH-releasing peptides (GHRPs), Ipamorelin is highly selective
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