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For cagrilintide , Phase 2 data has shown meaningful weight loss when used as monotherapy, and the CagriSema combination (cagrilintide plus semaglutide) has entered Phase 3 trials under the REDEFINE programme by Novo Nordisk

Price variations across countries highlight market disparities, Wegovy costs $1,349 monthly in the United States compared to $280 in Japan

[8] However, these findings come from limited, early-phase human studies and should not be taken as established clinical evidence

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