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demonstrated that baicalin inhibits airway smooth muscle cell proliferation and airway remodeling-associated gene expression, including IL13, vascular endothelial growth factor, TGF1, matrix metalloproteinases (MMP) 9, and tissue inhibitor of metalloproteinase 1 via the MAPK and RAS signaling pathways, implicating a role in preventing airway remodeling [213]

223,224 In contrast, Triphala , though widely used in Ayurveda, lacks adequate safety data and is not recommended in pregnancy because its laxative components (e.g., Haritaki ) may promote downward flow and raise miscarriage risks

& Satija, R

Oxford Monographs on Medical Genetics

Gene knockout A gene deletion mutant was constructed from E