When compared with DPP4 inhibitors, the risk was 7.8 cases per 10,000 among GLP-1 users versus 4.2 cases per 10,000 among those taking DPP4 drugs
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Recognizing Demographical Limitations : The authors explicitly note that because this mechanistic trial was executed solely in male mouse models, future trials must include female subjects to verify if the same microbiome-endocannabinoid pathway regulates mood across both sexes