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A compound that activates glucagon receptors, increasing hepatic fat oxidation and overall energy expenditure through metabolic stimulation
After weight loss, ghrelin levels increase (promoting hunger), while peptide YY and natural GLP-1 levels decrease (reducing satiety signals)
All other OMMs, but not liraglutide and semaglutide, exerted significant favorable effects on systolic blood pressure and some (phentermine plus topiramate, tirzepatide and orlistat) on diastolic blood pressure (Table 1)
diastolic, 1.07 mmHg) and reduced circulating lipids (total cholesterol, 0.30 mmol/l
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