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Injections bypass digestion entirely, while supplements rely on it

Although the effects of B12 vitamin injections are often temporary, it is crucial to check with a healthcare expert about the best method of administering the injections to ensure that they are as effective as possible

Central appetite suppression: Amylin crosses blood-brain barrier Activates area postrema (brainstem) Also acts on nucleus accumbens Direct satiety signaling Reduces desire to eat Different brain pathways than GLP-1 3

Funding This work was supported by the Universitat de Valncia (UV-INV-AE-1560151)

Li J, Jia B, Cheng Y, Song Y, Li Q, Luo C (2022) Targeting molecular mediators of ferroptosis and oxidative stress for neurological disorders