Researchers reviewing the literature around this compound can use the peer-reviewed resources below for additional context on mechanism of action, signaling pathways, and controlled laboratory research applications: Pickart et al
However, it's always wise to consult with a healthcare professional before starting any new supplement regimen, especially if you have pre-existing medical conditions or take medications
Therefore, our present observations indicate that L-citrulline is indeed a precursor to L-arginine formation which subsequently increases circulating levels of NOx, and that recycling of L-citrulline to L-arginine may maintain substrate concentration in favor of NO synthesis [Citation19]
Paulis L, Rajkovicova R, Simko F
LA pre-treatment (at 1:8000 ratio, with the wash-out step) did not affect the c-met binding-affinity of HGF before or after exposure to peroxynitrite at the same 1:2000 ratio as the LASSS pre-treatment (Figure 1d, lanes 4 and 7 )