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The C20 fatty acid is two carbons longer than the C18 chain in semaglutide, and the dual gamma-Glu spacer provides additional length and flexibility to the linker
Metabolism 101:154001 Rezaei S, Tabrizi R, Nowrouzi-Sohrabi P, Jalali M, Atkin SL, Al-Rasadi K et al (2021) GLP-1 receptor agonist effects on lipid and liver profiles in patients with nonalcoholic fatty liver disease: systematic review and meta-analysis
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