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PAM is a truly fascinating enzyme because its the only enzyme we have thats capable of a chemical process called amidation, which increases the half-life or the potency of biologically active peptides, Gloyn said
It could be due to the underestimated accumulation in tubular cells (renal tissue compartment in the model), as there are some indications of possible active reabsorption from the tubular lumen [13]
B.Olde DaminkS
Those who suffer from other dietary distresses like Crohns or stomach ulcers are also more likely to have low levels of Vitamin B12 absorption due to their illness and even their medications
PMID: 27088927
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