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ROS-induced NO inactivation can impair vascular endothelial function, contributing to various pathologies like atherosclerosis, hypertension, cardiovascular disease, and central nervous system disorders (27, 28)

DNA Damage ROS are reported to be mutagenic and can oxidatively damage DNA [106108] by causing strand breaks and modifications of bases, including the oxidation of guanine residues into 8-hydroxy 2-deoxyguanosine (8-OHdG)

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