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The plasma half-life is estimated at 30-60 minutes, though biological effects on gene expression persist for hours to days
For instance, higher circulating levels of TMAO have been associated with gastric cancer risk, particularly among males [4, 28]
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50,51 GIP infusion reduced aortic plaque formation, intra-plaque macrophage accumulation, and foam cell formation in diabetic mice, while its overexpression stabilizes the atherosclerotic plaque in non-diabetic animals
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