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Despite the advances in technology and insulin delivery over the past several decades, less than a third of adults with type 1 diabetes in England and Wales achieve a target HbA 1c of 58 mmol/mol [7.5%] [8], and only 20% of patients in the US T1D Exchange Registry achieved HbA 1c 53 mmol/mol [7.0%] [9]

Together, they ensure maximum cellular energy efficiency - particularly important for high-energy organs like the heart and muscles

The study showed a 20% risk reduction of the primary outcome in the GLP-1 RA arm (HR 0.80