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Given the progressive nature of Put-GABA down-regulation in DA/GABA striatal neurons with chronic ethanol consumption, as well as potential diversion of these nitrogen substrates toward NO synthesis (Figure 1), it could be worthwhile to examine whether promoting polyamine synthesis in striatal DA/GABA neurons impacts ethanol withdrawal symptoms

Higher cellular NAD+ was reported in preclinical work

In online forums, people have credited the peptide with boosting energy and curbing pain

(Id also first consider CIRS and MSH levels for gut health first)

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