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Further work is necessary to characterize the differences between GIPR agonism and antagonism and their impact on these molecular signalling pathways in the CNS

So, Secher asked, does that mean that these are the only regions that are activated by GLP-1 receptor agonists? She and her team do not believe that this is the case, she said, because when you have interaction with one neuron, this can communicate to many other neurons in deeper layers of the brain. To test whether that was happening, her team used c-Fos, a protein that can be used as a marker for neuronal activation