The FDA previously allowed compounded tirzepatide to be made due to a national shortage, but that shortage has been resolved, and pharmacies and outsourcing facilities are no longer allowed to compound, distribute, or dispense compounded GLP-1 medications, including tirzepatide
There have also been studies suggesting a slightly elevated risk of thyroid C-cell tumors.
GLP-1s, branded as Ozempic or Wegovy, are injectable medications that, combined with a healthy diet, exercise, and other lifestyle modifications, can help you control your portions, avoid unhealthy food cravings, and become a fitter, healthier version of yourself
The medication is part of a comprehensive treatment plan that includes personalized nutrition and lifestyle advice to ensure that the medical weight loss is sustainable and healthy
GLP-1 receptor agonists were initially developed to improve glycemic control in type 2 diabetes by enhancing insulin secretion and inhibiting glucagon release, with additional effects on appetite regulation and gastric emptying later recognized as clinically relevant (Meloni et al