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Br J Sports Med, 37: 100-105

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It is a 47-residue synthetic peptide constructed as a D-retro-inverso (DRI) analog: the primary sequence is reversed and each amino acid is substituted with its D-enantiomer, an arrangement that approximates the topological side-chain presentation of the parent L-peptide while conferring markedly greater resistance to proteolytic degradation in typical aqueous and biological buffer systems used at the bench

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Nrf2 expression was increased after deletion of MST1, whereas silencing of Nrf2 abolished the protective effects of Mst1 deletion on nasal epithelium survival and mitochondrial homeostasis (Song et al., 2019)

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