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In MCF-7 cancer cells, the overexpression of CAT affects their proliferation and migration and reduces their sensitivity to anticancer treatment [25]

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Patnoe said diabetes care and education specialists should screen patients with diabetes for eating disorder thoughts and behaviors before and after starting GLP-1 therapy, and therapy should start at the lowest dose possible where hunger signals are maintained, and titration should be slow

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The researchers thought that combining that mechanism with GLP-1s effect of suppressing appetite could be an especially potent approach, and GLP-1 could also offset glucagons effect of raising blood sugar

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