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The relevance of this enzyme is illustrated by the fact that global SOD2 deficiency leads to neonatal death in mice ( c plus cytochrome c oxidase system (Okado-Matsumoto and Fridovich, 2001)

This effect is part of the entero-insular axis of glucose homeostasis and is estimated to be responsible for at least 50% of insulin secretion [2, 3]

Although the role of FoxO3a varies across different biological conditions and therapeutic contexts, current studies have highlighted its potential as both a diagnostic and therapeutic target for OA

Innate immune inflammatory cell death: PANoptosis and PANoptosomes in host defense and disease

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