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It supports arguments that the drug manufacturer should have developed a safer drug or disclosed the risk in warnings, labeling, or during marketing

10.1016/j.yfrne.2014.05.002 43 GarberA.HenryR.RatnerR.Garcia-HernandezP

This crucial physical barrier effectively segregates gut microbiota from epithelial cells, preventing direct bacterial contact and subsequent immune system activation

In plain English: most peptides plug into a receptor on the cell surface and trigger a signal from there