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In IBD mouse models fed a high-fat, high-sugar diet, prolonged HFD intake not only induces gut microbiota dysbiosis but also compromises the integrity of the intestinal mucosal barrier, increasing intestinal permeability

And as always, the patient's expectations should be calibrated to what the evidence actually supports

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Your body produces it, but levels decline sharply with age and that drop tracks with thinner skin, slower healing, and less collagen