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SDS (to 1.1%) was added to the same cuvette and the solution was heated to 55C to denature the enzyme

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Consistently, we found that the left ventricular wall thickness (LVWT) of rats in TAC group was elevated, compared to those of rats in Sham group, but the LVWT of rats in TAC + semaglutide group was lessen by HE staining, compared to those of rats in TAC group (Fig

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This absence of direct evidence is unsurprising given berberine's status as a dietary supplement rather than a pharmaceutical agent, which limits its inclusion in formal drug interaction studies