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Standard titration spans 46 weeks from initiation to therapeutic dose
It remains the leading cause of ESKD in adults, with the global prevalence of DM in adult ESKD patients reaching 29.7% in 2015 [7]
Both are GHRH-receptor agonists that raise endogenous GH and IGF-1, but tesamorelin has far stronger and more recent human data than sermorelin
The gut absorbs only 6001,000 ml of fluid per hour at best too slow when dehydration is severe and symptoms are escalating
Its natural role is to coordinate the body's response to a meal: stimulating insulin secretion, suppressing glucagon, slowing the rate at which the stomach empties its contents into the small intestine, and signaling to the brain that energy has arrived and appetite can be reduced
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