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Given the high frequency of musculoskeletal problems in individuals with clEDS (Supplementary Table 1), we propose that coordination of care and follow-up for patients with clEDS lie with (pediatric) rheumatology and if available with specialized EhlersDanlos services

All serum parameters were higher in the Diane-35 group compared to the metformin and glutathione groups (metformin vs Diane-35 for IL-6

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RFP fluorescence (excitation= 584 nm, emission= 607 nm) and mCherry fluorescence (excitation= 587 nm, emission 610 nm) was measured every 5 min for 13 h

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