Large randomized trials designed to detect rare adverse events are mostly absent in this area
Mutations in NDMARs subunits are associated with neurodevelopmental disorders
(To read their article, click HERE) When you hear about blood clots in surgery, we are not talking about normal clotting needed to stop bleeding
However, in PD, abnormal iron accumulation in glial cells and dopaminergic neurons has been observed, with iron content strongly correlated with disease severity (249)
Zeng T, Li J, Xie L, Dong Z, Chen Q, Huang S, Xie S, Lai Y, Li J, Yan W, Wang Y, Xie Z, Hu C, Zhang J, Kuang S, Song Y, Gao L, Lv Z (2023) Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression