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The mean half-life of lamotrigine in these subjects was 31.2 hours (range: 24.5 to 43.4 hours), and the mean clearance was 0.40 mL/min/kg (range: 0.26 to 0.48 mL/min/kg)

The idea is that this could, in theory, lead to a small bump in calorie burning

Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR