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If you have a history of pancreatitis, your prescriber will weigh this risk carefully and monitor for symptoms (severe abdominal pain radiating to the back, nausea, vomiting)
Singh A, Nissen SE
If any of these occur, seek emergency medical care immediately
On one hand, IR leads to abnormal glucose uptake and oxidation, reduced glycogen synthesis, and decreased ability to inhibit lipid metabolism, resulting in glucose metabolism imbalance
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