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Those receiving orlistat experienced an average weight loss of 4.1 kg, and those receiving placebo lost 2.8 kg

Tumour growth delay ( T C ) was calculated by subtracting the median time to reach evaluation size (750 mg) of the treated group by the median time to evaluation size of the control group

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This study shows that adipose inflammation-stimulated lipolysis increases the influx of acetyl-CoA into the liver, which activates pyruvate carboxylase and promotes hepatic gluconeogenesis, leading to hyperglycaemia