IGF1 LR3 provides more direct receptor activation with fewer endocrine effects, though head-to-head comparisons are limited
886 The intestinal microbiota metabolite capsiate is negatively correlated with cartilage degeneration score in OA mice, and capsiate reduces ferroptosis dependent osteoarthritis both in vivo and in vitro, through activation of SLC2A1 and inhibition of HIF-1
Riddell EASLEASDEASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD): Executive Summary European Association for the Study of the Liver, European Association for the Study of Diabetes & European Association for the Study of Obesity Consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes - published online 24/06/2024 Moshe Phillip, Peter Achenbach, Ananta Addala, Anastasia Albanese-ONeill, Tadej Battelino, Kirstine J
I'm gonna talk about GLP ones, but I'm not a cheerleader for GLP ones
Apweiler M, Wilke Saliba S, Streyczek J, Normann C, Hellwig S, Brase S, et al