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The extracellular Km toward carnitine, measured in different experimental systems, ranges from 8 to 80 M depending on different species and/or tissues
However, its use is restricted to certified opioid treatment programs (OTPs), and it carries a risk of misuse, requiring close supervision
To facilitate the calculations and analysis, an artificial chimera molecule was built using the X-ray fragments found in subpockets A-C in PDB:6FP4 and PDB:6FTC and connected by a short CH 2 CH 2 linker
alcohol disrupts this balance
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